Gynecology Oncology
Tahereh Ashrafganjoei; nooshin amjadi; Robabeh Taheripanah; Hamed talayeh; maryam Talayeh; Nasim Noorinasab
Articles in Press, Accepted Manuscript, Available Online from 26 April 2024
Abstract
Introduction: The administration of tamoxifen to post-menopausal patients with breast cancer may lead to vaginal bleeding, necessitating a thorough understanding of associated factors. Our objective was to investigate sonographic, hysteroscopic, and pathologic findings in breast cancer patients experiencing ...
Read More
Introduction: The administration of tamoxifen to post-menopausal patients with breast cancer may lead to vaginal bleeding, necessitating a thorough understanding of associated factors. Our objective was to investigate sonographic, hysteroscopic, and pathologic findings in breast cancer patients experiencing vaginal bleeding following tamoxifen use.Methods: In this cross-sectional study, we evaluated women with post-menopausal breast cancer reporting vaginal bleeding while undergoing tamoxifen treatment for more than six months. Data collection involved a checklist encompassing ultrasonographic, hysteroscopic, and pathologic findings.Results: The study included 100 patients with a mean age of 56.2 ± 2.9 years and a mean endometrial thickness of 14.5 ± 3.4 mm. Notably, 25% of the patients exhibited abnormally large uterine size. Ultrasonography revealed polyps and myomas in 36% and 15% of cases, respectively. Positive hysteroscopy findings were observed in 72%, comprising polyps in 36%, hyperplasia in 32%, and atrophy in 4%. Pathological assessment identified abnormal features in 31% as polyps, 34% as hyperplasia, 4% as atrophy, and 5% as cancerous lesions.Conclusion: Patients who received tamoxifen had high endometrial thickness due to endometrial polyp, it seems that clinicians can consider using hysteroscopy with dilation and curettage in these patients.
Gynecology Oncology
Tahereh Ashraf Ganjoei; Maryam Talayeh; Noushin Afsharmoghadam; Ali Reza Norouzi; Somayyeh Noei Teymoordash
Volume 7, Issue 6 , September and October 2022, , Pages 583-586
Abstract
Paratubal cysts account for 5-20% of all adnexal lesions. Malignant modifications seldom arise in the paratubal cysts that are usually known as primary carcinomas of fallopian tube. Paratubal borderline tumors are very infrequent conditions and until now only sixteen cases of primary paratubal borderline ...
Read More
Paratubal cysts account for 5-20% of all adnexal lesions. Malignant modifications seldom arise in the paratubal cysts that are usually known as primary carcinomas of fallopian tube. Paratubal borderline tumors are very infrequent conditions and until now only sixteen cases of primary paratubal borderline tumors have been previously reported in the literature. Herein, we describe a rare paratubal serous borderline tumor occurring in a woman of reproductive age and provide insights into its management. A 32-year-old woman referred to Imam Hussein Hospital, Tehran with chief complaint of amenorrhea for the last year and transvaginal sonography (TVS) report indicating a 68×74 mm persistent right adnexal cyst from 10 months ago. The patient was candidate for laparotomy and due to the report of paratubal serous borderline tumor in frozen section she underwent right total salpingectomy and infracolic omentectomy. No evidence of recurrence or metastasis was observed after 3 years of follow up. Persistent adnexal cysts need to be evaluated precisely even in young women in order to rule out the malignancy of fallopian tubes.
Gynecology Oncology
Tahereh Ashrafganjoei; Maryam Talayeh; Somayeh Noei Teymoordash; Mohammad Hashemi Bahremani; Hamed talayeh
Volume 7, Issue 1 , September and October 2021, , Pages 59-62
Abstract
Uterine adenosarcoma (UA) is an infrequent malignancy which contains the epithelium of benign glands and malignant mesenchymal elements. Low-grade adenosarcoma has a sarcomatous part that is uniformly low grade. Uterine adenosarcoma includes 8% of all uterine sarcomas and less than 0.2% of uterine neoplasms. ...
Read More
Uterine adenosarcoma (UA) is an infrequent malignancy which contains the epithelium of benign glands and malignant mesenchymal elements. Low-grade adenosarcoma has a sarcomatous part that is uniformly low grade. Uterine adenosarcoma includes 8% of all uterine sarcomas and less than 0.2% of uterine neoplasms. It is more common in perimenopausal or postmenopausal women. Due to the rarity of uterine adenosarcoma, limited information is available to help guide treatment.A 33-year-old woman, who had one child referred to ???? with a complaint of abnormal uterine bleeding for one year; the sonography reported a polyp in fundal cavity of uterus. The patient underwent hysteroscopy and curettage. The pathology examination revealed uterine adenosarcoma which led to a total hysterectomy and bilateral salpingo-oophorectomy.Abnormal uterine bleeding is the most common symptom of UA. At a young age there is a possibility of misdiagnosis. Hysteroscopy should also be performed if symptomatic or enlarge polypoid lesions are diagnosed preoperatively.
Obstetrics and Gynecology
Tahereh Ashrafganjoei; Atyeh Bahman; Somayyeh Noei Teymoordash; Soheila Aminimoghaddam; Abdolali Ebrahimi; Maryam Talayeh
Volume 6, Issue 3 , June 2021, , Pages 105-109
Abstract
Background & Objective: Endometrial carcinoma is the most common malignancy of the female genital tract, which most often affects postmenopausal women. The ovaries may be active when a patient has endometrial cancer, so removing an ovary can worsen a patient's quality of life. On the other hand, ...
Read More
Background & Objective: Endometrial carcinoma is the most common malignancy of the female genital tract, which most often affects postmenopausal women. The ovaries may be active when a patient has endometrial cancer, so removing an ovary can worsen a patient's quality of life. On the other hand, a complete surgical staging in endometrial cancer includes oophorectomy since 1988. There has been some research to assess whether an oophorectomy should be performed and in which cases, ovaries can be preserved.Materials & Methods: Aim of this study was to evaluate the coexistence of ovarian involvement in endometrioid endometrial carcinoma. In this study, we evaluated 180 patients with endometrioid endometrial cancer patients who were surgically staged at Imam Hossein Hospital between 2004 and 2017.Results: Mean age of subjects of the study was 56.78 ±10.59. Forty-six of patients (25.6 %) were less than 50 years old and 74.4 % (134) were older than 50. Twenty out of 180 (11.1 %) of them had ovarian involvement (one of them had simultaneous ovarian tumor) and 11 (55%) of these cases were less than 50 years old. In 55 % (11) patients, the involved ovaries were less than 5 cm with grossly normal appearance, lymph nodes metastases were detected in 3 out of 20 (15 %) of them although their ovarian size were 4, 4.5 and 6.5 cm. In 10 (50 %) of them, deep myometrial invasion was detected.Conclusion: In endometrial cancer staging, ovarian preservation could be a challenging decision and a real controversy which needs more researches.
Tahereh Ashrafganjoei; Donya Khosravi
Volume 2, Issue 3 , September and October 2017
Abstract
Introduction: The aim of this study was to describe clinical findings of prolapse of fallopian tube to vaginal vault following abdominal hysterectomy for multiple leiomyomas of uterine and to correlate it with other features.
Case Presentation: A patient with history of leiomyomas and abnormal uterine ...
Read More
Introduction: The aim of this study was to describe clinical findings of prolapse of fallopian tube to vaginal vault following abdominal hysterectomy for multiple leiomyomas of uterine and to correlate it with other features.
Case Presentation: A patient with history of leiomyomas and abnormal uterine bleeding was admitted with abdominal pain and scheduled for abdominal hysterectomy. Intra operative inspection showed multiple leiomyomas of uterine. One year after operation of total abdominal hysterectomy, the patient presented with abdominal pain, dyspareunia, and purulent vaginal discharge and therefore, referred to our center for further evaluation. In the vaginal examination, a protruding red mass with fibrotic fimberia was observed. The right fallopian tube (FT) with its fimbria prolapsed to vaginal vault as a granulation tissue was removedfrom vaginal cuff and sent to pathology. The pathologist reported fallopian tube tissue. Post-operative course was uneventful and the patient was discharged on 2nd day of post hysterectomy with good general condition. Six-month follow-up showed abolished purulent discharge. The site of resected vaginal cuff was intact in vaginal examination.
Conclusions: Intra vaginal prolapse of the fallopian tube is a rare sequel of hysterectomy. Clinicians should be aware of this disregarded sequel when dealing with postysterectomy vaginal discharge.